Naip5 nlrc4 inflammasome activation - Innate immunity: the activation of the inflammasome
Structural mechanisms of inflammasome Inflammasome assembly requires activation of (2012) Formation and structure of a NAIP5-NLRC4 inflammasome induced
Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Critical function for Naip5 in inflammasome activation by a …
. . Cryo electron tomography of the Naip5-Nlrc4 inflammasome. 5AJ2 Cryo electron Little is known about the conformational changes involved in NLR activation
NAIP5 in triggering NLRC4 inflammasome activation. NAIP5 and NLRC4 were then co-expressed in 293T cells and their possible interactions were investigated.
NAIP2 initiates NLRC4 activation and polymerization in a domino-like reaction (Fig. 3B). NAIP5/His-MBP-NLRC4Δ inflammasome system because of
NAIPs determines inflammasome specificity NAIP5–NLRC4 activation by flagellin. Consistent with the autoinhibitory function of the leucine-rich repeats