Arrestin orchestrates cross-talk between GPCRs to
SRE reporter assay for MAPK/ERK signaling via RTK and GPCR Jey Cheng, Pete Stecha, Keith Wood, and Frank Fan MAPK/ERK pathway.
Receptor-specific regulation of ERK1/2 activation by
. . sequestration of ERK induced by another GPCR. Activation the G protein-coupled receptor-beta-arrestin 1 by MEK/ERK pathway is necessary for
Different Patterns of Akt and ERK Feedback Activation in
View pathway information and literature references for your pathway. and the ERK activation cascade is G protein-coupled receptor microarrays for drug
QIAGEN - GeneGlobe Pathways - GPCR Pathway
GPCR reagents and kits for research monitoring GPCR pathway activation, reporter gene The assay will measure ERK 1/2 activation by either recombinant or
Minireview: Targeting GPCR Activated ERK Pathways for
G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis. pathway activation G-protein coupled receptor 34 activates Erk
Pathway Central: GPCR Pathway - SABiosciences
It has become clear in recent years that multiple signal transduction pathways are employed upon GPCR activation. One of the major cellular effectors activated by GPCRs is extracellular signal-regulated kinase (ERK).
Phospho-ERK (Thr202/Tyr204), Advanced phospho-ERK
β-arrestin 1 and β-arrestin 2 are well-known negative regulators of G-protein-coupled receptor (GPCR) signaling. Upon GPCR activation, β-arrestins translocate to the cell membrane and bind to the agonist-occupied receptors.
GPCR-jacking: from a new route in RTK signalling to a
β-arrestin–dependent pathway. G protein–dependent ERK ERK activation is slower in onset and lasts GPCR and β-arrestin interaction. 12 Here we have
GPCR Signaling To MAPK/ERK Phospho Antibody Array
Abstract. Regulation of the ERK1/2 cascade is one of the most studied functions of arrestins and illustrates many of the features that enable them to function as GPCR-regulated scaffolds.